alpha 1 Adrenergic Receptor anticorps

N° du produit ABIN272286

Cet anticorps anti-alpha 1 Adrenergic Receptor Polyclonal Lapin (ABIN272286) détecte spécifiquement alpha 1 Adrenergic Receptor dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour alpha 1 Adrenergic Receptor anticorps (ABIN272286)

Antigène: alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha 1 Adrenergic Receptor est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-alpha 1 Adrenergic Receptor anticorps

Specificité: This antibody detects endogenous levels of AR-alpha1A protein. (region surrounding Gln365)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur alpha 1 Adrenergic Receptor

Antigène: alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))

Autre désignation: alpha-1A Adrenergic Receptor

Sujet: Alpha1A-adrenergic receptors (alpha1A-ARs) mediate actions in the sympathetic nervous system through the binding of the catecholamines, epinephrine and norepinephrine. alpha1A-AR couples to Gq/11 and regulates blood pressure due to changes in vascular tone and cardiac output. Alternative splicing of the ADRA1A gene generates four isoforms with distinct C-termini, and the different expression profile of these subtypes produces distinct patterns of activation. alpha1A-AR transcripts are abundant in heart, brain, liver and prostate. alpha1A-AR transcript sizes of 6.0, 4.0, 3.0, and 2.0 kb have been detected in liver. Transcripts of 6.0, 4.0 and 3.0 kb have been detected in heart, and transcripts of 6.0 and 4.0 kb have been detected in prostate.Synonyms: ADRA1A, ADRA1C, Alpha 1A-adrenoceptor, Alpha 1A-adrenoreceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c

Poids moléculaire: approx. 51 kDa

ID gène: 148

NCBI Accession: NP_000671

UniProt: P35348

Pathways: AMPK Signaling