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Cytokeratin 18 anticorps (FITC)

L’anticorps Souris Monoclonal anti-Cytokeratin 18 a été validé pour IF, FACS et IHC (p). Il convient pour détecter Cytokeratin 18 dans des échantillons de Humain. Il y a 2+ publications disponibles.
N° du produit ABIN272330

Aperçu rapide pour Cytokeratin 18 anticorps (FITC) (ABIN272330)

Antigène

Voir toutes Cytokeratin 18 (KRT18) Anticorps
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivité

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  • 74
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  • 18
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Humain

Hôte

  • 194
  • 158
  • 3
  • 1
  • 1
  • 1
Souris

Clonalité

  • 217
  • 138
  • 3
Monoclonal

Conjugué

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  • 10
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Cet anticorp Cytokeratin 18 est conjugé à/à la FITC

Application

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

DC-10
  • Specificité

    The antibody DC-10 reacts with Cytokeratin 18 (45 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.

    Réactivité croisée (Details)

    Species reactivity (tested):Human.

    Purification

    Protein A Chromatography

    Immunogène

    Human breast carcinoma cell line PMC-42.

    Isotype

    IgG1
  • Indications d'application

    Further Comments: Flow Cytometry analysis and Immunofluorescence (5-10 μg/mL).

    Restrictions

    For Research Use only
  • Concentration

    0.1 mg/mL

    Buffer

    PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade BSA (Protease free)

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Vojt?sek, Stasková, Nenutil, Lauerová, Kovarík, Rejthar, Bártková, Bártek: "Monoclonal antibodies recognizing different epitopes of cytokeratin No.18." dans: Folia biologica, Vol. 35, Issue 6, pp. 373-82, (1990) (PubMed).

    Kovarík, Rejthar, Lauerová, Vojt?sek, Bártková: "Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread." dans: International journal of cancer. Supplement = Journal international du cancer. Supplement, Vol. 3, pp. 50-5, (1989) (PubMed).

  • Antigène

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    Autre désignation

    Cytokeratin 18

    Sujet

    Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families. Cytokeratin 18 belongs to type I family (acidic cytokeratins).Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18

    ID gène

    3875

    NCBI Accession

    NP_000215

    UniProt

    P05783

    Pathways

    Apoptose, Caspase Cascade in Apoptosis
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