Cytokeratin 18 anticorps (FITC)
Aperçu rapide pour Cytokeratin 18 anticorps (FITC) (ABIN272330)
Antigène
Voir toutes Cytokeratin 18 (KRT18) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The antibody DC-10 reacts with Cytokeratin 18 (45 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Protein A Chromatography
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Immunogène
- Human breast carcinoma cell line PMC-42.
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Isotype
- IgG1
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Indications d'application
- Further Comments: Flow Cytometry analysis and Immunofluorescence (5-10 μg/mL).
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Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade BSA (Protease free)
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Monoclonal antibodies recognizing different epitopes of cytokeratin No.18." dans: Folia biologica, Vol. 35, Issue 6, pp. 373-82, (1990) (PubMed).
: "Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread." dans: International journal of cancer. Supplement = Journal international du cancer. Supplement, Vol. 3, pp. 50-5, (1989) (PubMed).
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: "Monoclonal antibodies recognizing different epitopes of cytokeratin No.18." dans: Folia biologica, Vol. 35, Issue 6, pp. 373-82, (1990) (PubMed).
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- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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Autre désignation
- Cytokeratin 18
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Sujet
- Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families. Cytokeratin 18 belongs to type I family (acidic cytokeratins).Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
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ID gène
- 3875
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NCBI Accession
- NP_000215
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UniProt
- P05783
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Pathways
- Apoptose, Caspase Cascade in Apoptosis
Antigène
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