OTUB1 anticorps
Aperçu rapide pour OTUB1 anticorps (ABIN2728034)
Antigène
Voir toutes OTUB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- Homo sapiens OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1
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Purification
- Purified from mouse ascites fluids by affinity chromatography
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Immunogène
- Full length human recombinant protein of human OTUB1(NP_060140) produced in HEK293T cell.
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Isotype
- IgG1
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Indications d'application
- WB 1:2000, IHC 1:150, FLOW 1:100,
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Commentaires
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The concentration of the product may vary between diferrent lots.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5-1.0 mg/mL
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Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
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Autre désignation
- OTUB1
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Sujet
- The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 31.1 kDa
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ID gène
- 55611
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NCBI Accession
- NM_017670
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HGNC
- 55611
Antigène
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