PSMD2 anticorps

N° du produit ABIN2729981

Cet anticorps anti-PSMD2 Monoclonal Souris (Clone 1A12) (ABIN2729981) détecte spécifiquement PSMD2 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PSMD2 anticorps (ABIN2729981)

Antigène: PSMD2 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PSMD2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 1A12

Détail du produit anti-PSMD2 anticorps

Attributs du produit: Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (PSMD2)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant peotein of human PSMD2(NP_002799) produced in HEK293T cell.

Isotype: IgG2a

Information d'application

Indications d'application: WB 1:2000, IF 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur PSMD2

Antigène: PSMD2 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))

Autre désignation: PSMD2

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.

Poids moléculaire: 100 kDa

ID gène: 5708

NCBI Accession: NM_002808

HGNC: 5708

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway