TP53I3 anticorps

N° du produit ABIN2734080

Cet anticorps Souris Monoclonal détecte spécifiquement TP53I3 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TP53I3 anticorps (ABIN2734080)

Antigène: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TP53I3 est non-conjugé

Application: Western Blotting (WB)

Clone: 3E3

Détail du produit anti-TP53I3 anticorps

Attributs du produit: Homo sapiens tumor protein p53 inducible protein 3 (TP53I3), transcript variant 2

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human TP53I3(NP_671713) produced in HEK293T cell.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:2000,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur TP53I3

Antigène: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Autre désignation: TP53I3

Sujet: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 35.4 kDa

ID gène: 9540

NCBI Accession: NM_147184

HGNC: 9540

Pathways: Signalisation p53