TP53I3 anticorps
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- Antigène Voir toutes TP53I3 Anticorps
- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TP53I3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- Homo sapiens tumor protein p53 inducible protein 3 (TP53I3), transcript variant 2
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogène
- Full length human recombinant protein of human TP53I3(NP_671713) produced in HEK293T cell.
- Clone
- 3B11
- Isotype
- IgG1
- Top Product
- Discover our top product TP53I3 Anticorps primaire
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- Indications d'application
- WB 1:2000, IHC 1:150,
- Commentaires
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
- Autre désignation
- TP53I3 (TP53I3 Produits)
- Synonymes
- anticorps MGC82892, anticorps MGC146409, anticorps PIG3, anticorps tumor protein p53 inducible protein 3, anticorps tumor protein p53 inducible protein 3 S homeolog, anticorps Tp53I3, anticorps quinone oxidoreductase PIG3, anticorps TP53I3, anticorps tp53i3.S, anticorps tp53i3, anticorps tp53I3
- Sujet
- The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.
- Poids moléculaire
- 35.4 kDa
- ID gène
- 9540
- NCBI Accession
- NM_147184
- HGNC
- 9540
- Pathways
- Signalisation p53
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