Chromogranin A anticorps

N° du produit ABIN2739940

Cet anticorps anti-Chromogranin A est un anticorps Souris Monoclonal détectant Chromogranin A dans IF, IHC, FACS, WB, ELISA, IHC (p) et IP. Adapté pour Humain, Rat, Souris, Singe et Porc.

Aperçu rapide pour Chromogranin A anticorps (ABIN2739940)

Antigène: Chromogranin A (CHGA)

Reactivité: Humain, Rat, Souris, Singe, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Chromogranin A est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Clone: LK2H10

Détail du produit anti-Chromogranin A anticorps

Specificité: Human CHGA / Chromogranin A

Aucune reactivité croisée: Cobaye, Lapin, Mouton

Purification: Protein G purified

Immunogène: Human pheochromocytoma cells were used as the immunogen for this Chromogranin A antibody.

Type of Immunogen: Cells

Isotype: IgG1 kappa

Information d'application

Indications d'application: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

Usage: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong chromogranin A antibody staining and absence of keratin antibody staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin. ELISA: Order BSA-free antibody format for coating.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C to 8°C.

Détails sur Chromogranin A

Antigène: Chromogranin A (CHGA)

Autre désignation: CHGA / Chromogranin A

Sujet: Name/Gene ID: CHGA

Synonyms: CHGA, Chromogranin A, Chromogranin-A, Pancreastatin, Pituitary secretory protein I, Vasostatin I, SP-I, Vasostatin II

ID gène: 1113

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling