Prostate Specific Antigen anticorps
Aperçu rapide pour Prostate Specific Antigen anticorps (ABIN2742421)
Antigène
Voir toutes Prostate Specific Antigen (PSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Human KLK3 / PSA
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Purification
- Protein G purified
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Immunogène
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Prostate Specific Antigen from human sperm plasma.
Type of Immunogen: Purified protein -
Isotype
- IgG1 kappa
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Indications d'application
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Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)
Usage: This antibody recognizes a single protein of 33-34 kDa, identified as the Prostate specific antigen. This PSA antibody is highly specific and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. Prostate specific antigen is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign hyperplasia. Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA Buffer, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes. ELISA: Order BSA-free PSA antibody format for coating. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2°C to 8°C.
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- Prostate Specific Antigen (PSA)
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Autre désignation
- KLK3 / PSA
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Sujet
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Name/Gene ID: KLK3
Subfamily: Serine S1
Family: Protease
Synonyms: KLK3, APS, Gamma-seminoprotein, Kallikrein-3, Kallikrein-related peptidase 3, P-30 antigen, Prostate specific antigen, Prostate-specific antigen, PSA, Semenogelase, KLK2A1, Seminin -
ID gène
- 354
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Pathways
- Système du Complément
Antigène
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