BAFF anticorps

N° du produit ABIN2745514

Cet anticorps anti-BAFF est un anticorps Monoclonal produit chez le Souris, détectant BAFF dans IP et Func. Convient pour Souris.

Aperçu rapide pour BAFF anticorps (ABIN2745514)

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BAFF est non-conjugé

Application: Immunoprecipitation (IP), Functional Studies (Func)

Clone: Sandy-2

Détail du produit anti-BAFF anticorps

Specificité: Recognizes mouse BAFF.

Réactivité croisée: Souris

Pureté: >95 % (SDS-PAGE)

niveau d'endotoxine: <0.01EU/μg purified protein (LAL test, Lonza).

Immunogène: Recombinant mouse BAFF.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 10 % glycerol.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur BAFF

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Autre désignation: BAFF

Sujet: BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

UniProt: Q9WU72

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response