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Caspase 4 anticorps

CASP4 Reactivité: Souris, Rat WB, ELISA, IP, FACS Hôte: Rat Monoclonal 8A5 unconjugated
N° du produit ABIN2745522
  • Antigène Voir toutes Caspase 4 (CASP4) Anticorps
    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
    Reactivité
    • 59
    • 33
    • 15
    • 13
    • 1
    Souris, Rat
    Hôte
    • 78
    • 11
    • 1
    • 1
    • 1
    Rat
    Clonalité
    • 77
    • 14
    Monoclonal
    Conjugué
    • 54
    • 15
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Caspase 4 est non-conjugé
    Application
    • 74
    • 28
    • 27
    • 12
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)
    Specificité
    Recognizes mouse and rat full-length caspase-11 protein. Detects two bands of ~38 kDa and ~43 kDa by Western blot.
     Réactivité croisée
    Souris, Rat (Rattus)
    Pureté
    >95 % (SDS-PAGE)
    niveau d'endotoxine
    <0.1EU/μg purified protein (LAL test, Lonza).
    Immunogène
    Recombinant mouse caspase-11 (p20 fragment).
    Clone
    8A5
    Isotype
    IgG1
    Top Product
    Discover our top product CASP4 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Date de péremption
    12 months
  • Antigène
    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
    Autre désignation
    Caspase-11 (CASP4 Produits)
    Synonymes
    anticorps ICE(rel)II, anticorps ICEREL-II, anticorps ICH-2, anticorps Mih1/TX, anticorps TX, anticorps Casp11, anticorps CASP13, anticorps CASP1, anticorps CASP4, anticorps Caspl, anticorps ich-3, anticorps Casp4, anticorps caspase 4, anticorps caspase 4, apoptosis-related cysteine peptidase, anticorps caspase-4, anticorps CASP4, anticorps Casp4, anticorps LOC100731032
    Sujet
    Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.
    UniProt
    P70343
    Pathways
    Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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