Podoplanin anticorps

N° du produit ABIN2745557

Cet anticorps Hamster Monoclonal détecte spécifiquement Podoplanin dans WB, IHC, ELISA et IP. Il présente une réactivité envers Souris.

Aperçu rapide pour Podoplanin anticorps (ABIN2745557)

Antigène: Podoplanin (PDPN)

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp Podoplanin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Clone: RTD4E10

Détail du produit anti-Podoplanin anticorps

Specificité: Recognizes mouse podoplanin.

Réactivité croisée: Souris

Aucune reactivité croisée: Humain

Réactivité croisée (Details): Does not cross-react with human podoplanin.

Purification: Protein G purified.

Immunogène: Murine thymic stromal cell line.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL.

Concentration: Lot specific

Buffer: Lyophilized.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détails sur Podoplanin

Antigène: Podoplanin (PDPN)

Autre désignation: Podoplanin

Sujet: Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Pathways: Dicarboxylic Acid Transport