PDE4A anticorps

N° du produit ABIN2747099

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE4A dans WB, IHC, IF, ELISA, IP, ICC et CM. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Poulet et Singe. Il a été cité dans 13+ publications.

Aperçu rapide pour PDE4A anticorps (ABIN2747099)

Antigène: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Reactivité: Humain, Souris, Rat, Poulet, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE4A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Confocal Microscopy (CM)

Détail du produit anti-PDE4A anticorps

Purification: Affinity Purified

Immunogène: Synthetic peptide common to most PDE4 subtypes: PDE4A, PDE4D, PDE4B

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.62 μg/μL

Références pour anticorps anti-PDE4A (ABIN2747099)

Lee, Shin, Hong: "The Regulatory Role of Rolipram on Inflammatory Mediators and Cholinergic/Adrenergic Stimulation-Induced Signals in Isolated Primary Mouse Submandibular Gland Cells." dans: Mediators of inflammation, Vol. 2016, pp. 3745961, (2017) (PubMed).

Wang, Zhang, Liu, Zhao, Zhang, Yuan, An, Li, Wang, Qin, Wilson, ODonnell, Zhang, Li: "RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects." dans: British journal of pharmacology, Vol. 168, Issue 4, pp. 1001-14, (2013) (PubMed).

Castiglione, Bergamini, Russo, La Croce, Castagna, Colciago, Salonia, Rigatti, Montorsi, Hedlund: "Inhibition of phosphodiesterase 4 enhances clitoral and vaginal blood flow responses to dorsal clitoral nerve stimulation or PGE1 in anesthetized female rats." dans: The journal of sexual medicine, Vol. 10, Issue 4, pp. 939-50, (2013) (PubMed).

Muzaffar, Jeremy, Angelini, Shukla: "NADPH oxidase 4 mediates upregulation of type 4 phosphodiesterases in human endothelial cells." dans: Journal of cellular physiology, Vol. 227, Issue 5, pp. 1941-50, (2012) (PubMed).

Li, Cheng, Huang, Conti, Wilson, ODonnell, Zhang: "Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 1, pp. 172-83, (2011) (PubMed).

Yagi, Tada, Kitazato, Tamura, Satomi, Nagahiro: "Ibudilast inhibits cerebral aneurysms by down-regulating inflammation-related molecules in the vascular wall of rats." dans: Neurosurgery, Vol. 66, Issue 3, pp. 551-9; discussion 559, (2010) (PubMed).

Dodd-o, Hristopoulos, Kibler, Gutkowska, Mukaddam-Daher, Gonzalez, Welsh-Servinsky, Pearse: "The role of natriuretic peptide receptor-A signaling in unilateral lung ischemia-reperfusion injury in the intact mouse." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 4, pp. L714-23, (2008) (PubMed).

Uckert, Oelke, Stief, Andersson, Jonas, Hedlund: "Immunohistochemical distribution of cAMP- and cGMP-phosphodiesterase (PDE) isoenzymes in the human prostate." dans: European urology, Vol. 49, Issue 4, pp. 740-5, (2007) (PubMed).

Ückert, Oelke, Albrecht, Stief, Jonas, Hedlund: "Immunohistochemical description of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human labia minora." dans: The journal of sexual medicine, Vol. 4, Issue 3, pp. 602-608, (2007) (PubMed).

Creighton, Zhu, Alexeyev, Stevens: "Spectrin-anchored phosphodiesterase 4D4 restricts cAMP from disrupting microtubules and inducing endothelial cell gap formation." dans: Journal of cell science, Vol. 121, Issue Pt 1, pp. 110-9, (2007) (PubMed).

Oelke, Hedlund, Albrecht, Ellinghaus, Stief, Jonas, Andersson, Uckert: "Expression of cAMP and cGMP-phosphodiesterase isoenzymes 3, 4, and 5 in the human clitoris: immunohistochemical and molecular biology study." dans: Urology, Vol. 67, Issue 5, pp. 1111-6, (2006) (PubMed).

Uckert, Hedlund, Waldkirch, Sohn, Jonas, Andersson, Stief: "Interactions between cGMP- and cAMP-pathways are involved in the regulation of penile smooth muscle tone." dans: World journal of urology, Vol. 22, Issue 4, pp. 261-6, (2005) (PubMed).

Uckert, Oelke, Waldkirch, Stief, Albrecht, Tröger, Jonas, Andersson, Hedlund: "Cyclic adenosine monophosphate and cyclic guanosine monophosphate-phosphodiesterase isoenzymes in human vagina: relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nerves." dans: Urology, Vol. 65, Issue 3, pp. 604-10, (2005) (PubMed).

Détails sur PDE4A

Antigène: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Autre désignation: PDE4

Pathways: cAMP Metabolic Process