Cadherin 5 anticorps
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- Antigène Voir toutes Cadherin 5 (CDH5) Anticorps
- Cadherin 5 (CDH5)
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Cadherin 5 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- The mouse monoclonal antibody 55-7H1 recognizes a calcium-independent extracellular epitope on CD144 (VE-cadherin, cadherin 5), an adhesion molecule expressed on endothelial cells.
- Réactivité croisée (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Human endothelial cells
- Clone
- 55-7H1
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CDH5 Anticorps primaire
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- Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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Establishment of a human in vitro model of the outer blood-retinal barrier." dans: Journal of anatomy, Vol. 211, Issue 6, pp. 707-16, (2007) (PubMed).
: "Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members." dans: Blood, Vol. 105, Issue 8, pp. 3169-77, (2005) (PubMed).
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Establishment of a human in vitro model of the outer blood-retinal barrier." dans: Journal of anatomy, Vol. 211, Issue 6, pp. 707-16, (2007) (PubMed).
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- Antigène
- Cadherin 5 (CDH5)
- Autre désignation
- CD144 (CDH5 Produits)
- Synonymes
- anticorps 7B4, anticorps AA408225, anticorps Cd144, anticorps VE-Cad, anticorps VECD, anticorps VEcad, anticorps Vec, anticorps wu:fc88a07, anticorps CD144, anticorps cadherin-5, anticorps cadherin 5, anticorps CDH5, anticorps Cdh5, anticorps cdh5
- Sujet
- Cadherin 5,CD144 / VE-cadherin (cadherin 5) is the major cadherin that is present at endothelial junctions. It is also strictly endothelial specific. Under vascular permeability increasing conditions (and also in capillaries and veins) CD144 is being phosphorylated, which promotes its rapid and reversible internalization. On the contrary, binding of p120 catenin (delta1 catenin) maintains CD144 localization at the plasma membrane, which stabilizes the junction and reduces vascular permeability.,Cadherin 5, CDH5, 7B4, VE-cadherin
- ID gène
- 1003
- UniProt
- P33151
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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