phosphodiesterase 5A, cGMP-Specific (PDE5A) (AA 120-170), (phosphorylated) anticorps

Détails pour le produit réf. ABIN2750986
Antigène
  • CGB-PDE
  • CN5A
  • PDE5
  • PDE5A2
  • Cgbpde
  • Cn5n
  • Pde5
  • Pde5a1
  • PDE5A
  • pde5a
  • cgb-pde
  • cn5a
  • pde5
  • pde5a1
  • phosphodiesterase 5A
  • phosphodiesterase 5A, cGMP-specific
  • phosphodiesterase 5A S homeolog
  • phosphodiesterase 5A, cGMP-specific, b
  • PDE5A
  • Pde5a
  • pde5a.S
  • pde5ab
  • pde5a
Épitope
AA 120-170, phosphorylated
10
3
2
2
2
2
2
1
Reactivité
Boeuf (Vache), Humain, Souris, Porc, Rat (Rattus)
52
19
17
7
4
4
2
1
1
1
1
Hôte
Lapin
41
8
5
Clonalité
Polyclonal
Conjugué
Inconjugué
4
3
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
40
27
16
14
11
9
7
6
3
2
1
Options
Immunogène Phosphorylated synthetic peptide common to all PDE5A variants taken within amino acid region 120-170 on human PDE5A protein.
Blocking Peptide Blocking peptide for this product available: ABIN2750988
Isotype IgG
Purification Affinity Purified
Antigène
Autre désignation PDE5A (PDE5A Antibody Extrait)
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling
Restrictions For Research Use only
Format Liquid
Concentration 1.0-1.25 μg/μL
Produit citée dans: Rajagopal, Nalli, Kumar, Bhattacharya, Hu, Mahavadi, Grider, Murthy: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." dans: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, 2015 (PubMed).

Bautista Niño, Durik, Danser, de Vries, Musterd-Bhaggoe, Meima, Kavousi, Ghanbari, Hoeijmakers, ODonnell, Franceschini, Janssen, De Mey, Liu, Shanahan, Franco, Dehghan, Roks: "Phosphodiesterase 1 regulation is a key mechanism in vascular aging." dans: Clinical science (London, England : 1979), Vol. 129, Issue 12, pp. 1061-75, 2015 (PubMed).

Luong, Rey-Perra, Vadivel, Gilmour, Sauve, Koonen, Walker, Todd, Gressens, Kassiri, Nadeem, Morgan, Eaton, Dyck, Archer, Thébaud: "Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia." dans: Circulation, Vol. 123, Issue 19, pp. 2120-31, 2011 (PubMed).

Monfort, Muñoz, Felipo: "Chronic hyperammonemia in vivo impairs long-term potentiation in hippocampus by altering activation of cyclic GMP-dependent-protein kinase and of phosphodiesterase 5." dans: Journal of neurochemistry, Vol. 94, Issue 4, pp. 934-42, 2005 (PubMed).

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