CCR3 anticorps (APC)

N° du produit ABIN2752003

Cet anticorps anti-CCR3 est un anticorps Souris Monoclonal détectant CCR3 dans FACS. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour CCR3 anticorps (APC) (ABIN2752003)

Antigène: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCR3 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: 5E8

Détail du produit anti-CCR3 anticorps (APC)

Fonction: Anti-Hu CD193 APC

Specificité: The mouse monoclonal antibody 5E8 recognizes an extracellular epitope of CD193 (chemokine receptor 3), an approximately 41 kDa protein expressed above all in eosinophils and basophils.

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: human CD193 transfectants

Isotype: IgG2b kappa

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-CCR3 (APC) (ABIN2752003)

Morshed, Hlushchuk, Simon, Walls, Obata-Ninomiya, Karasuyama, Djonov, Eggel, Kaufmann, Simon, Yousefi: "NADPH oxidase-independent formation of extracellular DNA traps by basophils." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5314-23, (2014) (PubMed).

Détails sur CCR3

Antigène: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Autre désignation: CD193

Sujet: C-C motif chemokine receptor 3,CD193 / CCR3 is a G-protein coupled receptor for several chemokines, namely CCL11 (eotaxin), CCL26 (eotaxin-3), CCL7 (MCP-4), or CCL5 (RANTES). It is highly expressed on eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. CD193 is the key eosinophil chemokine receptor responsible for regulation of eosinophil migration and function. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.,CCR3, CKR3, CMKBR3, CC-CKR-3

ID gène: 1232

UniProt: P51677