BCL2L1 anticorps (AA 1-209) (FITC)
Aperçu rapide pour BCL2L1 anticorps (AA 1-209) (FITC) (ABIN2753384)
Antigène
Voir toutes BCL2L1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-209
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Bcl-2-like protein 1 protein (1-209AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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Autre désignation
- BCL2L1
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Sujet
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Background: Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Ref.17 Ref.19 Ref.20 Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F1F0 activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles.
Aliases: Apoptosis regulator Bcl X antibody, Apoptosis regulator Bcl-X antibody, Apoptosis regulator BclX antibody, B cell lymphoma 2 like antibody, B2CL1_HUMAN antibody, Bcl 2 like 1 protein antibody, Bcl X antibody, Bcl xL antibody, BCL XL/S antibody, Bcl xS antibody, Bcl-2-like protein 1 antibody, Bcl2 Like 1 antibody, Bcl2 related gene antibody, Bcl2-L-1 antibody, BCL2L antibody, Bcl2l1 antibody, BCLX antibody, BclXL antibody, BclXs antibody, DKFZp781P2092 antibody, PPP1R52 antibody, Protein phosphatase 1 regulatory subunit 52 antibody
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UniProt
- Q07817
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Pathways
- Apoptose, Negative Regulation of intrinsic apoptotic Signaling
Antigène
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