ICMT anticorps (Middle Region)

N° du produit ABIN2773889

Cité dans 1 publication. Cet anticorps anti-ICMT Polyclonal Lapin (ABIN2773889) détecte spécifiquement ICMT dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Cobaye, Lapin, Boeuf (Vache), Chien, Cheval et Saccharomyces cerevisiae.

Aperçu rapide pour ICMT anticorps (Middle Region) (ABIN2773889)

Antigène: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Reactivité: Humain, Rat, Souris, Cobaye, Lapin, Boeuf (Vache), Chien, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ICMT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ICMT anticorps

Épitope: Middle Region

Fonction: ICMT Antibody - middle region

Séquence: GSNFNHVVQN EKSDTHTLVT SGVYAWFRHP SYVGWFYWSI GTQVMLCNPI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ICMT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ICMT

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46894-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ICMT (ABIN2773889)

Nuthalapaty, Lu, Ramin, Nuthalapaty, Ramin, Ramsey: "Is there a preferred gestational age threshold of viability?: a survey of maternal-fetal medicine providers." dans: The journal of maternal-fetal & neonatal medicine, Vol. 20, Issue 4, pp. 293-7, (2007) (PubMed).

Détails sur ICMT

Antigène: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Autre désignation: ICMT

Sujet:

Background Information: ICMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.

Gene Name: Isoprenylcysteine carboxyl methyltransferase

Alternative Symbols: PCMT, PPMT, PCCMT, HSTE14, MST098, MSTP098

Protein Name: Protein-S-isoprenylcysteine O-methyltransferase

Poids moléculaire: 32kDa

ID gène: 23463

NCBI Accession: NP_036537

UniProt: O60725