ME3 anticorps (N-Term)

N° du produit ABIN2773921

L’anticorps anti-ME3 Polyclonal Lapin est utilisé pour la détection de ME3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio) et Mouton. Il a été validé pour WB.

Aperçu rapide pour ME3 anticorps (N-Term) (ABIN2773921)

Antigène: ME3 (Malic Enzyme 3, NADP(+)-Dependent, Mitochondrial (ME3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ME3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ME3 anticorps

Épitope: N-Term

Fonction: ME3 Antibody - N-terminal region

Séquence: PGPARPVPLK KRGYDVTRNP HLNKGMAFTL EERLQLGIHG LIPPCFLSQD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ME3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ME3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48511-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ME3

Antigène: ME3 (Malic Enzyme 3, NADP(+)-Dependent, Mitochondrial (ME3))

Autre désignation: ME3

Sujet:

Background Information: Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. ME3 is a mitochondrial NADP(+)-dependent isoform. Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Gene Name: Malic enzyme 3, NADP(+)-dependent, mitochondrial

Alternative Symbols: NADP-ME

Protein Name: NADP-dependent malic enzyme, mitochondrial

Poids moléculaire: 67kDa

ID gène: 10873

NCBI Accession: NP_001014811

UniProt: Q16798

Pathways: L'effet Warburg