RABGGTA anticorps (N-Term)

N° du produit ABIN2773937

Il existe 2+ publications pour ce produit. L’anticorps anti-RABGGTA Polyclonal Lapin est utilisé pour la détection de RABGGTA dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin. Il a été validé pour WB.

Aperçu rapide pour RABGGTA anticorps (N-Term) (ABIN2773937)

Antigène: RABGGTA (Rab Geranylgeranyltransferase, alpha Subunit (RABGGTA))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RABGGTA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RABGGTA anticorps

Épitope: N-Term

Fonction: RABGGTA Antibody - N-terminal region

Séquence: ELAFTDSLIT RNFSNYSSWH YRSCLLPQLH PQPDSGPQGR LPEDVLLKEL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RABGGTA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RABGGTA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109774

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RABGGTA (ABIN2773937)

Arora, Syed, Machhadieh, McKenna, Kowluru: "Rab-geranylgeranyl transferase regulates glucose-stimulated insulin secretion from pancreatic ? cells." dans: Islets, Vol. 4, Issue 5, pp. 354-8, (2012) (PubMed).

Lachance, Cartier, Génier, Munger, Germain, Labrecque, Parent: "Regulation of ?2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: modulation of Rab geranylgeranylation by the receptor." dans: The Journal of biological chemistry, Vol. 286, Issue 47, pp. 40802-13, (2011) (PubMed).

Détails sur RABGGTA

Antigène: RABGGTA (Rab Geranylgeranyltransferase, alpha Subunit (RABGGTA))

Autre désignation: RABGGTA

Sujet:

Targeted Subunit: alpha

Background Information: RABGGTA belongs to the protein prenyltransferase subunit alpha family and contains 6 PFTA repeats. RABGGTA catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.

Gene Name: Rab geranylgeranyltransferase, alpha subunit

Alternative Symbols: PTAR3

Protein Name: Geranylgeranyl transferase type-2 subunit alpha

Poids moléculaire: 65kDa

ID gène: 5875

NCBI Accession: NP_878256

UniProt: Q92696