CDR2 anticorps (N-Term)

N° du produit ABIN2773981

Détail du produit anti-CDR2 anticorps

Antigène: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDR2 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Séquence: MLAENLVEEF EMKEDEPWYD HQDLQQDLQL AAELGKTLLD RNTELEDSVQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CDR2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CDR2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 454 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDR2

Antigène: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Autre désignation: CDR2 (CDR2 Produits)

Synonymes: anticorps CDR62, anticorps Yo, anticorps cdr2, anticorps MGC69206, anticorps CDR2, anticorps AA617262, anticorps RGD1310578, anticorps cerebellar degeneration related protein 2, anticorps cerebellar degeneration related protein 2 L homeolog, anticorps cerebellar degeneration-related 2, anticorps cerebellar degeneration-related protein 2, anticorps cerebellar degeneration related protein 2 like, anticorps CDR2, anticorps cdr2, anticorps cdr2.L, anticorps Cdr2, anticorps CDR2L, anticorps LOC101060399

Sujet: Cdr2 normally sequesters c-Myc in the neuronal cytoplasm, thereby down-regulating c-Myc activity, and suggest a mechanism whereby inhibition of cdr2 function by autoantibodies in PCD may contribute to Purkinje neuronal.
Alias Symbols: CDR62, Yo
Protein Interaction Partner: SMARCE1, CEP57L1, KANSL1, CCDC153, C4orf46, TXLNA, ALS2CR11, C1orf216, HAUS1, ANKRD36BP1, TCHP, FAM161A, ENKD1, FAM110A, LENG1, SCNM1, SH2D4A, LIN37, RCOR3, TBC1D22B, WDYHV1, CCHCR1, AMOTL2, FZR1, RSPH14, CHIC2, MRPL28, TMCC2, HDAC4, EIF4E2, TTR, COX5B, T
Protein Size: 454

Poids moléculaire: 52 kDa

ID gène: 1039

NCBI Accession: NM_001802, NP_001793

UniProt: Q01850