PNKP anticorps (N-Term)

N° du produit ABIN2774011

Cet anticorps anti-PNKP est un anticorps Lapin Polyclonal détectant PNKP dans WB. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye et Cheval.

Aperçu rapide pour PNKP anticorps (N-Term) (ABIN2774011)

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNKP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PNKP anticorps

Épitope: N-Term

Séquence: MGEVEAPGRL WLESPPGGAP PIFLPSDGQA LVLGRGPLTQ VTDRKCSRTQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PNKP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PNKP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 521 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PNKP

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Autre désignation: PNKP

Sujet: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
Alias Symbols: PNK, MCSZ, EIEE10
Protein Interaction Partner: ZNF639, IKZF1, TNIP1, ZBTB14, RPA3, RPA2, RPA1, EED, rev, KDM1A, SUV39H1, HNRNPU, GZMK, XRCC6, CDK11B, PARP1, MCM3, SMAD5, LIG4, XRCC1, TCOF1, SSRP1, PRKDC, NRD1, NASP, MCM5, C18orf25, UBE2O, GEMIN4, AGTPBP1, PNKP, SUPT16H, VPRBP, NOLC1, TRIM26, XRCC5, XR
Protein Size: 521

Poids moléculaire: 57 kDa

ID gène: 11284

NCBI Accession: NM_007254, NP_009185

UniProt: Q96T60

Pathways: Réparation de l'ADN, Nucleotide Phosphorylation