PNKP anticorps (N-Term)

N° du produit ABIN2774011

Détail du produit anti-PNKP anticorps

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNKP est non-conjugé

Application: Western Blotting (WB)

Séquence: MGEVEAPGRL WLESPPGGAP PIFLPSDGQA LVLGRGPLTQ VTDRKCSRTQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PNKP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PNKP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 521 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PNKP

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Autre désignation: PNKP (PNKP Produits)

Synonymes: anticorps EIEE10, anticorps MCSZ, anticorps PNK, anticorps Tb06.28P18.320, anticorps 21.m03011, anticorps 1810009G08Rik, anticorps polynucleotide kinase 3'-phosphatase, anticorps hypothetical protein, anticorps polynucleotide kinase 3'- phosphatase, anticorps PNKP, anticorps Pnkp, anticorps Tc00.1047053507017.50, anticorps Tc00.1047053505807.190, anticorps Tb927.6.1580, anticorps BBOV_IV000690, anticorps CC1G_05202, anticorps PGTG_20262, anticorps PGTG_18987, anticorps pnkp.S, anticorps pnkp

Sujet: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
Alias Symbols: PNK, MCSZ, EIEE10
Protein Interaction Partner: ZNF639, IKZF1, TNIP1, ZBTB14, RPA3, RPA2, RPA1, EED, rev, KDM1A, SUV39H1, HNRNPU, GZMK, XRCC6, CDK11B, PARP1, MCM3, SMAD5, LIG4, XRCC1, TCOF1, SSRP1, PRKDC, NRD1, NASP, MCM5, C18orf25, UBE2O, GEMIN4, AGTPBP1, PNKP, SUPT16H, VPRBP, NOLC1, TRIM26, XRCC5, XR
Protein Size: 521

Poids moléculaire: 57 kDa

ID gène: 11284

NCBI Accession: NM_007254, NP_009185

UniProt: Q96T60

Pathways: Réparation de l'ADN, Nucleotide Phosphorylation