PNKP anticorps (N-Term)

N° du produit ABIN2774011

Cet anticorps anti-PNKP Polyclonal Lapin (ABIN2774011) détecte spécifiquement PNKP dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye et Cheval.

Aperçu rapide pour PNKP anticorps (N-Term) (ABIN2774011)

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNKP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PNKP anticorps

Épitope: N-Term

Fonction: PNKP Antibody - N-terminal region

Séquence: MGEVEAPGRL WLESPPGGAP PIFLPSDGQA LVLGRGPLTQ VTDRKCSRTQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PNKP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PNKP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52311-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PNKP

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Autre désignation: PNKP

Sujet:

Background Information: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Gene Name: Polynucleotide kinase 3'-phosphatase

Alternative Symbols: PNK, AOA4, MCSZ, CMT2B2, EIEE10

Protein Name: Bifunctional polynucleotide phosphatase/kinase

Poids moléculaire: 57kDa

ID gène: 11284

NCBI Accession: NP_009185

UniProt: Q96T60

Pathways: Réparation de l'ADN, Nucleotide Phosphorylation