Spastin anticorps (Middle Region)

N° du produit ABIN2774193

Cet anticorps anti-Spastin Polyclonal Lapin (ABIN2774193) détecte spécifiquement Spastin dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache), Chien, Chévre et Poisson zèbre (Danio rerio).

Aperçu rapide pour Spastin anticorps (Middle Region) (ABIN2774193)

Antigène: Spastin (SPAST)

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache), Chien, Chévre, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Spastin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Spastin anticorps

Épitope: Middle Region

Fonction: SPAST Antibody - middle region

Séquence: RVLVMGATNR PQELDEAVLR RFIKRVYVSL PNEETRLLLL KNLLCKQGSP

Homologie: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SPAST. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human SPAST

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57602-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Spastin

Antigène: Spastin (SPAST)

Autre désignation: SPAST

Sujet:

Background Information: This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.

Gene Name: spastin

Alternative Symbols: FSP2, SPG4, ADPSP

Protein Name: Spastin

Poids moléculaire: 54kDa

ID gène: 6683

UniProt: Q9UBP0

Pathways: Dynamique des Microtubules, M Phase, Regulation of Cell Size