Caspase 6 anticorps (Middle Region)

N° du produit ABIN2774243

L’anticorps anti-Caspase 6 Polyclonal Lapin est utilisé pour la détection de Caspase 6 dans des échantillons de Humain, Souris et Porc. Il a été validé pour WB.

Aperçu rapide pour Caspase 6 anticorps (Middle Region) (ABIN2774243)

Antigène: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reactivité: Humain, Souris, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Caspase 6 anticorps

Épitope: Middle Region

Fonction: CASP6 Antibody - middle region

Séquence: QACRGNQHDV PVIPLDVVDN QTEKLDTNIT EVDAASVYTL PAGADFLMCY

Homologie: Human: 100%, Mouse: 82%, Pig: 77%

Attributs du produit: This is a rabbit polyclonal antibody against CASP6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CASP6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58994-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Caspase 6

Antigène: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Autre désignation: CASP6

Sujet:

Background Information: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.

Gene Name: Caspase 6, apoptosis-related cysteine peptidase

Alternative Symbols: MCH2

Protein Name: Caspase-6

Poids moléculaire: 33kDa

ID gène: 839

NCBI Accession: NP_001217

UniProt: P55212

Pathways: Apoptose, Caspase Cascade in Apoptosis