Caspase 6 anticorps (Middle Region)

N° du produit ABIN2774243

Détail du produit anti-Caspase 6 anticorps

Antigène: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Épitope: Middle Region

Reactivité: Humain, Souris, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 6 est non-conjugé

Application: Western Blotting (WB)

Séquence: QACRGNQHDV PVIPLDVVDN QTEKLDTNIT EVDAASVYTL PAGADFLMCY

Homologie: Human: 100%, Mouse: 82%, Pig: 77%

Attributs du produit: This is a rabbit polyclonal antibody against CASP6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CASP6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 293 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Caspase 6

Antigène: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Autre désignation: CASP6 (CASP6 Produits)

Synonymes: anticorps xCaspase-6, anticorps mch2, anticorps caspase-6, anticorps zgc:112960, anticorps CASP6, anticorps casp6, anticorps Mch2, anticorps mCASP-6, anticorps MCH2, anticorps caspase 6 L homeolog, anticorps caspase 6, anticorps caspase 6, apoptosis-related cysteine peptidase, anticorps group XIIA secretory phospholipase A2, anticorps caspase-6, anticorps casp6.L, anticorps casp6, anticorps CASP6, anticorps CpipJ_CPIJ017008, anticorps Casp6

Sujet: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
Alias Symbols: MCH2
Protein Interaction Partner: CASP6, XIAP, CRYAB, UBC, CASP3, RB1, IKBKG, PRKAB2, SP1, COPS6, SATB1, TAB1, MAPK6, PIN1, UBE4A, NUAK1, UBE4B, CHD3, PSME3, EIF2S1, CFLAR, PPL, NEDD4, SRP72, CASP8, CASP10, TRAF1, PSEN2, SRF, VIM, PRKCZ, MAPT, LMNB1, LMNA, KRT18, HTT, TOP1, DSP, PCYT1A, T
Protein Size: 293

Poids moléculaire: 33 kDa

ID gène: 839

NCBI Accession: NM_001226, NP_001217

UniProt: P55212

Pathways: Apoptose, Caspase Cascade in Apoptosis