AMACR anticorps (C-Term)

N° du produit ABIN2774297

L’anticorps Lapin Polyclonal anti-AMACR a été validé pour WB et IHC. Il convient pour détecter AMACR dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cheval, Lapin et Cobaye.

Aperçu rapide pour AMACR anticorps (C-Term) (ABIN2774297)

Antigène: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMACR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-AMACR anticorps

Épitope: C-Term

Séquence: IFDGTDACVT PVLTFEEVVH HDHNKERGSF ITSEEQDVSP RPAPLLLNTP

Homologie: Cow: 85%, Dog: 100%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Mouse: 77%, Pig: 85%, Rabbit: 82%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against AMACR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human AMACR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 382 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AMACR

Antigène: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Autre désignation: AMACR

Sujet: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Alias Symbols: CBAS4, RACE, RM, AMACRD
Protein Interaction Partner: UBC, PEX5,
Protein Size: 382

Poids moléculaire: 42 kDa

ID gène: 23600

NCBI Accession: NM_014324, NP_055139

UniProt: Q9UHK6

Pathways: Monocarboxylic Acid Catabolic Process