VPS4B anticorps (N-Term)

N° du produit ABIN2774320

Cet anticorps anti-VPS4B est un anticorps Lapin Polyclonal détectant VPS4B dans WB. Adapté pour Humain, Rat, Chien, Cobaye, Cheval, Lapin et Boeuf (Vache).

Aperçu rapide pour VPS4B anticorps (N-Term) (ABIN2774320)

Antigène: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Reactivité: Humain, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS4B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-VPS4B anticorps

Épitope: N-Term

Séquence: EKLKEYLKNK EKKAQKPVKE GQPSPADEKG NDSDGEGESD DPEKKKLQNQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against VPS4B. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 444 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur VPS4B

Antigène: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Autre désignation: VPS4B

Sujet: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18, the gene for the other resides on chromosome 16.
Alias Symbols: MIG1, SKD1, SKD1B, VPS4-2
Protein Interaction Partner: ZFYVE19, CHMP5, UBC, HTRA2, CHMP4A, TTLL12, AHCYL1, SSSCA1, YAP1, UBE4B, PDCD6IP, USP34, VPS26A, USP8, ZPR1, NUP214, TYMS, RAB5B, IGBP1, TTC9C, ZNF585B, UBQLN4, UBXN1, UBQLN1, CUL3, CHMP2A, CHMP1A, ELAVL1, BABAM1, CHMP1B, VPS4A, VPS4, LIP5,
Protein Size: 444

Poids moléculaire: 49 kDa

ID gène: 9525

NCBI Accession: NM_004869, NP_004860

UniProt: O75351

Pathways: Dynamique des Microtubules, CXCR4-mediated Signaling Events