KRT6A anticorps (C-Term)

N° du produit ABIN2774397

Cet anticorps Lapin Polyclonal détecte spécifiquement KRT6A dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Porc et Lapin.

Aperçu rapide pour KRT6A anticorps (C-Term) (ABIN2774397)

Antigène: KRT6A (Keratin 6A (KRT6A))

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KRT6A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KRT6A anticorps

Épitope: C-Term

Séquence: IIAEVKAQYE EIAQRSRAEA ESWYQTKYEE LQVTAGRHGD DLRNTKQEIA

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KRT6A. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 564 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KRT6A

Antigène: KRT6A (Keratin 6A (KRT6A))

Autre désignation: KRT6A

Sujet: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Alias Symbols: CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D
Protein Interaction Partner: TRIM54, KRT40, TFIP11, HGS, KRT38, SGTA, KRT31, KRT15, KRT13, KIFC3, GOLGA2, TRIM23, LGR4, EED, KDM1A, PAN2, Iqcb1, Nphp4, Cep290, Nphp1, Invs, UBC, ITGA4, ALB, UBASH3B, SHC1, GRB2, EPS15, CRK, AP2M1, CBL, CUL1, COPS5, CUL2, CUL5, CCDC85B, TCHP, CCDC53, K
Protein Size: 564

Poids moléculaire: 62 kDa

ID gène: 3853

NCBI Accession: NM_005554, NP_005545

UniProt: P02538