TOP1MT anticorps (C-Term)

N° du produit ABIN2774452

L’anticorps anti-TOP1MT Polyclonal Lapin est utilisé pour la détection de TOP1MT dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour TOP1MT anticorps (C-Term) (ABIN2774452)

Antigène: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOP1MT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TOP1MT anticorps

Épitope: C-Term

Fonction: TOP1MT Antibody - C-terminal region

Séquence: KKRRLLEKLQ EQLAQLSVQA TDKEENKQVA LGTSKLNYLD PRISIAWCKR

Homologie: Cow: 85%, Dog: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Yeast: 79%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against TOP1MT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TOP1MT

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66489-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TOP1MT

Antigène: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Autre désignation: TOP1MT

Sujet:

Background Information: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative Symbols: -

Protein Name: DNA topoisomerase I, mitochondrial

Poids moléculaire: 70kDa

ID gène: 116447

NCBI Accession: NP_443195

UniProt: Q969P6