TOP1MT anticorps (C-Term)

N° du produit ABIN2774452

Détail du produit anti-TOP1MT anticorps

Antigène: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio), Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOP1MT est non-conjugé

Application: Western Blotting (WB)

Séquence: KKRRLLEKLQ EQLAQLSVQA TDKEENKQVA LGTSKLNYLD PRISIAWCKR

Homologie: Cow: 85%, Dog: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Yeast: 79%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against TOP1MT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TOP1MT

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 601 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TOP1MT

Antigène: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Autre désignation: TOP1MT (TOP1MT Produits)

Synonymes: anticorps 2900052H09Rik, anticorps TOP1, anticorps topoisomerase (DNA) I, mitochondrial, anticorps DNA topoisomerase 1, mitochondrial, anticorps DNA topoisomerase I mitochondrial, anticorps TOP1MT, anticorps Top1mt

Sujet: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: -
Protein Interaction Partner: SUMO1, FSHR, UBC,
Protein Size: 601

Poids moléculaire: 70 kDa

ID gène: 116447

NCBI Accession: NM_052963, NP_443195

UniProt: Q969P6