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LGMN anticorps (Middle Region)

LGMN Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio), Mouton, Porc WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2774455
  • Antigène Voir toutes LGMN Anticorps
    LGMN (Legumain (LGMN))
    Épitope
    • 16
    • 12
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio), Mouton, Porc
    Hôte
    • 48
    • 7
    Lapin
    Clonalité
    • 49
    • 6
    Polyclonal
    Conjugué
    • 25
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LGMN est non-conjugé
    Application
    • 46
    • 25
    • 14
    • 8
    • 8
    • 7
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    ESSYACYYDE KRSTYLGDWY SVNWMEDSDV EDLTKETLHK QYHLVKSHTN
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against LGMN. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of Human LGMN
    Top Product
    Discover our top product LGMN Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 433 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    LGMN (Legumain (LGMN))
    Autre désignation
    LGMN (LGMN Produits)
    Synonymes
    anticorps AEP, anticorps LGMN1, anticorps PRSC1, anticorps AI746452, anticorps AU022324, anticorps Prsc1, anticorps MGC64351, anticorps cb173, anticorps cb460, anticorps sb:cb173, anticorps zgc:76953, anticorps wu:fa98g05, anticorps wu:fj92g08, anticorps lgmn, anticorps MGC88980, anticorps DELTA VACUOLAR PROCESSING ENZYME, anticorps DELTAVPE, anticorps delta vacuolar processing enzyme, anticorps legumain, anticorps legumain L homeolog, anticorps delta vacuolar processing enzyme, anticorps Legumain, anticorps LGMN, anticorps Lgmn, anticorps lgmn.L, anticorps lgmn, anticorps DELTA-VPE, anticorps MBOO_RS07785, anticorps Odosp_3582, anticorps LOC569153
    Sujet
    This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined.
    Alias Symbols: AEP, LGMN1, PRSC1
    Protein Interaction Partner: USP17L2, TRAF6, USP17L9P, SUMO1, UBC, NEDD8, LAMC3, ACIN1, IGF2BP3, HNRNPR, FBXO6, ISG15, LGMN,
    Protein Size: 433
    Poids moléculaire
    48 kDa
    ID gène
    5641
    NCBI Accession
    NM_005606, NP_005597
    UniProt
    Q99538
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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