BCL2L1 anticorps (N-Term)

N° du produit ABIN2774598

Cet anticorps anti-BCL2L1 est un anticorps Lapin Polyclonal détectant BCL2L1 dans WB. Adapté pour Humain, Porc, Mouton, Chien, Boeuf (Vache) et Lapin.

Aperçu rapide pour BCL2L1 anticorps (N-Term) (ABIN2774598)

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivité: Humain, Porc, Mouton, Chien, Boeuf (Vache), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2L1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BCL2L1 anticorps

Épitope: N-Term

Séquence: LVVDFLSYKL SQKGYSWSQF SDVEENRTEA PEGTESEMET PSAINGNPSW

Homologie: Cow: 92%, Dog: 100%, Human: 100%, Pig: 92%, Rabbit: 84%, Sheep: 92%

Attributs du produit: This is a rabbit polyclonal antibody against BCL2L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human BCL2L1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 233 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur BCL2L1

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Autre désignation: BCL2L1

Sujet: BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.
Alias Symbols: BCLX, BCL2L, BCLXL, BCLXS, Bcl-X, bcl-xL, bcl-xS, PPP1R52, BCL-XL/S
Protein Interaction Partner: BCL2L1, BCL2, BAX, BAD, BMF, BBC3, CASP8AP2, BECN1, UBC, TPT1, TP53BP2, ced-9, ced-4, PGAM5, CDKN2A, CASP1, BCL2L11, HRK, PMAIP1, BIK, BID, PARK2, PINK1, BAK1, RAD9A, AKT1, Mapk1, ATXN3, CLU, BCAP31, CRYAB, CRYAA, BFAR, PPP1CC, PPP1CA, ACTB, UBR1, METTL23
Protein Size: 233

Poids moléculaire: 26 kDa

ID gène: 598

NCBI Accession: NM_138578, NP_612815

UniProt: Q07817

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling