CXCL12 anticorps (Middle Region)

N° du produit ABIN2774605

L’anticorps Lapin Polyclonal anti-CXCL12 a été validé pour WB. Il convient pour détecter CXCL12 dans des échantillons de Rat, Chien, Porc et Boeuf (Vache). Il y a 1 publication disponible.

Aperçu rapide pour CXCL12 anticorps (Middle Region) (ABIN2774605)

Antigène: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Reactivité: Rat, Chien, Porc, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCL12 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CXCL12 anticorps

Épitope: Middle Region

Séquence: VKHLKILNTP NCALQIVARL KNNNRQVCID PKLKWIQEYL EKALNKRFKM

Homologie: Cow: 90%, Dog: 100%, Pig: 100%, Rat: 90%

Attributs du produit: This is a rabbit polyclonal antibody against CXCL12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CXCL12

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 93 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CXCL12 (ABIN2774605)

Yin, Seeberger: "Applications of heparin and heparan sulfate microarrays." dans: Methods in enzymology, Vol. 478, pp. 197-218, (2010) (PubMed).

Détails sur CXCL12

Antigène: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Autre désignation: CXCL12

Sujet: Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.
Alias Symbols: IRH, PBSF, SDF1, TLSF, SDF1A, SDF1B, TPAR1, SCYB12
Protein Interaction Partner: DAZAP2, CXCR4, CXCL12, DPP4, CD4, FN1, ELANE, MMP2, CTSG, VCAN, PF4,
Protein Size: 93

Poids moléculaire: 11 kDa

ID gène: 6387

NCBI Accession: NM_000609, NP_000600

UniProt: P48061

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling