MCM7 anticorps (N-Term)

N° du produit ABIN2774617

L’anticorps Lapin Polyclonal anti-MCM7 a été validé pour WB. Il convient pour détecter MCM7 dans des échantillons de Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Cheval, Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour MCM7 anticorps (N-Term) (ABIN2774617)

Antigène: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Reactivité: Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Cheval, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MCM7 anticorps

Épitope: N-Term

Séquence: KYGNQLVRLA HREQVALYVD LDDVAEDDPE LVDSICENAR RYAKLFADAV

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MCM7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MCM7

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MCM7

Antigène: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Autre désignation: MCM7

Sujet: MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB.
Alias Symbols: CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146
Protein Interaction Partner: AK8, MIPOL1, C8orf34, USHBP1, MCMBP, CCDC102B, TRIM54, MBIP, UBQLN1, TRIM27, NAB2, KIFC3, GOLGA2, PNMA1, UBC, SP2, HAUS2, CEP250, CEP57, SUMO2, SUMO3, PCNA, STAU1, SUZ12, RNF2, MCM4, MCM2, HSP90AB1, PRMT1, PRRC1, CLUH, TOMM34, TRIM16, HYOU1, BAG3, MIB1, P
Protein Size: 389

Poids moléculaire: 42 kDa

ID gène: 4176

NCBI Accession: NM_182776, NP_877577

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA