ADAR anticorps (C-Term)

N° du produit ABIN2774647

Cet anticorps Lapin Polyclonal détecte spécifiquement ADAR dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Cobaye, Cheval et Lapin et a été mentionné dans 1 publication.

Aperçu rapide pour ADAR anticorps (C-Term) (ABIN2774647)

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ADAR anticorps

Épitope: C-Term

Séquence: RMGFTEVTPV TGASLRRTML LLSRSPEAQP KTLPLTGSTF HDQIAMLSHR

Homologie: Guinea Pig: 92%, Horse: 92%, Human: 92%, Mouse: 91%, Rabbit: 92%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ADAR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ADAR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1226 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ADAR (ABIN2774647)

Pan, Ye, Franco, Li, Yu, Zou, Zhang, Jiao, Lin: "Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study." dans: Journal of affective disorders, Vol. 109, Issue 1-2, pp. 75-82, (2008) (PubMed).

Détails sur ADAR

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Autre désignation: ADAR

Sujet: ADAR is responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: ADAR1, DRADA, DSH, DSRAD, G1P1, IFI-4, IFI4, K88dsRBP, p136, P136, K88DSRBP
Protein Interaction Partner: UBC, SUMO2, SUMO3, STAU1, STAU2, SUMO1, RPA3, RPA2, RPA1, ERG, SUZ12, EED, EZH2, BMI1, RNF2, rev, FBXO6, TARDBP, UBE2I, HDAC9, XPO1, WHSC1, TGM2, SNRPN, SNRPB, UPF1, DHX9, DDX17, HNRNPM, CAND1, CUL3, HNRNPA1, ELAVL1, HDAC5, tat, ADAR, HDLBP,
Protein Size: 1226

Poids moléculaire: 136 kDa

ID gène: 103

NCBI Accession: NM_001111, NP_001102

UniProt: P55265

Pathways: Protein targeting to Nucleus