DMRT1 anticorps (N-Term)

N° du produit ABIN2774657

Détail du produit anti-DMRT1 anticorps

Antigène: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Épitope: N-Term

Reactivité: Humain, Boeuf (Vache), Chien, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMRT1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PNDEAFSKPS TPSEAPHAPG VPPQGRAGGF GKASGALVGA ASGSSAGGSS

Réactivité croisée: Boeuf (Vache), Chien, Humain, Porc

Homologie: Cow: 78%, Dog: 85%, Human: 100%, Pig: 78%, Rabbit: 92%

Attributs du produit: This is a rabbit polyclonal antibody against DMRT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DMRT1

Information d'application

Indications d'application: WB Suggested Anti-DMRT1 Antibody Titration: 0.2-1 µg/mL
Positive Control: Human brain.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 373 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DMRT1

Antigène: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Autre désignation: DMRT1 (DMRT1 Produits)

Synonymes: anticorps DMT1, anticorps DMRT1, anticorps zgc:136676, anticorps dmrt1, anticorps dmrt1-alpha, anticorps dmt1, anticorps dmrt1-beta, anticorps xdmrt1, anticorps doublesex and mab-3 related transcription factor 1, anticorps doublesex and mab-3 related transcription factor 1 L homeolog, anticorps doublesex and mab-3 related transcription factor 1 S homeolog, anticorps DMRT1, anticorps Dmrt1, anticorps dmrt1, anticorps dmrt1.L, anticorps dmrt1.S

Sujet: The gene encodes the DMRT1 protein is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. This suggested that DMRT1 may be required for testis development.This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DMT1
Protein Interaction Partner: Dlg4, TRIM29,
Protein Size: 373

Poids moléculaire: 39 kDa

ID gène: 1761

NCBI Accession: NM_021951, NP_068770

UniProt: Q9Y5R6