FBXO21 anticorps (N-Term)

N° du produit ABIN2774725

Cet anticorps Lapin Polyclonal détecte spécifiquement FBXO21 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Chien, Lapin, Cobaye, Boeuf (Vache) et Saccharomyces cerevisiae.

Aperçu rapide pour FBXO21 anticorps (N-Term) (ABIN2774725)

Antigène: FBXO21 (F-Box Protein 21 (FBXO21))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cobaye, Boeuf (Vache), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO21 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-FBXO21 anticorps

Épitope: N-Term

Séquence: KEQFRVRWPS LMKHYSPTDY VNWLEEYKVR QKAGLEARKI VASFSKRFFS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%

Attributs du produit: This is a rabbit polyclonal antibody against FBXO21. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO21

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 621 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FBXO21

Antigène: FBXO21 (F-Box Protein 21 (FBXO21))

Autre désignation: FBXO21

Sujet: FBXO21 contains 1 F-box domain. It is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
Alias Symbols: DKFZp434G058, FBX21, FLJ90233, KIAA0875, MGC26682
Protein Interaction Partner: TP53, CDKN1A, SUMO1, SMURF1, NEDD8, UBC, COPS5, COPS6, CUL1, ELAVL1, CNTNAP4, TERF2, TERF1,
Protein Size: 621

Poids moléculaire: 71 kDa

ID gène: 23014

NCBI Accession: NM_015002, NP_055817

UniProt: O94952