UBR2 anticorps (C-Term)

N° du produit ABIN2774730

Cet anticorps anti-UBR2 Polyclonal Lapin (ABIN2774730) détecte spécifiquement UBR2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Lapin, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour UBR2 anticorps (C-Term) (ABIN2774730)

Antigène: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBR2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UBR2 anticorps

Épitope: C-Term

Fonction: UBR2 Antibody - C-terminal region

Séquence: QGLRRGNPLH LCKERFKKIQ KLWHQHSVTE EIGHAQEANQ TLVGIDWQHL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against UBR2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human UBR2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43188-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBR2

Antigène: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Autre désignation: UBR2

Sujet:

Background Information: Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM].

Gene Name: Ubiquitin protein ligase E3 component n-recognin 2

Alternative Symbols: C6orf133, bA49A4.1, dJ242G1.1, dJ392M17.3

Protein Name: E3 ubiquitin-protein ligase UBR2

Poids moléculaire: 200kDa

ID gène: 23304

NCBI Accession: NP_056070

UniProt: Q8IWV8