TRIM63 anticorps (Middle Region)

N° du produit ABIN2774803

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIM63 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour TRIM63 anticorps (Middle Region) (ABIN2774803)

Antigène: TRIM63 (Tripartite Motif Containing 63 (TRIM63))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM63 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRIM63 anticorps

Épitope: Middle Region

Séquence: EQLDKSTKLV ETAIQSLDEP GGATFLLTAK QLIKSIVEAS KGCQLGKTEQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TRIM63. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TRIM63

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 353 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRIM63

Antigène: TRIM63 (Tripartite Motif Containing 63 (TRIM63))

Autre désignation: TRIM63

Sujet: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.
Alias Symbols: FLJ32380, IRF, MURF1, MURF2, RNF28, SMRZ
Protein Interaction Partner: UBE2D3, UBE2D1, UBC, TRIM63, USP37, ANKIB1, EPN1, ATXN3, EPS15, DCAF6, LMCD1, ANKRD1, NOMO1, GMEB1, NEBL, PIAS3, MRPL19, MYOT, PIAS2, SQSTM1, TCAP, PIAS1, UXT, UQCRC1, TTN, TNNI3, TNNI2, TNNI1, GFM1, TRIM55, MRPL41, MYOZ1, NEB, NDUFA1, MYBPC3, MYBPC1, EIF
Protein Size: 353

Poids moléculaire: 40 kDa

ID gène: 84676

NCBI Accession: NM_032588, NP_115977

UniProt: Q969Q1