Annexin a1 anticorps (N-Term)

N° du produit ABIN2774833

Cité dans 2 publications. Cet anticorps anti-Annexin a1 Polyclonal Lapin (ABIN2774833) détecte spécifiquement Annexin a1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Cobaye, Chien et Boeuf (Vache).

Aperçu rapide pour Annexin a1 anticorps (N-Term) (ABIN2774833)

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivité: Humain, Souris, Rat, Cobaye, Chien, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Annexin a1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Annexin a1 anticorps

Épitope: N-Term

Fonction: ANXA1 Antibody - N-terminal region

Séquence: WFIENEEQEY VQTVKSSKGG PGSAVSPYPT FNPSSDVAAL HKAIMVKGVD

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 83%, Rat: 82%

Attributs du produit: This is a rabbit polyclonal antibody against ANXA1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094714

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Annexin a1 (ABIN2774833)

Ishida, Yamasaki, Yukizaki, Nishiyama, Tsubouchi, Okayama, Kataoka et al.: "Carnosol, rosemary ingredient, induces apoptosis in adult T-cell leukemia/lymphoma cells via glutathione depletion: proteomic approach using fluorescent two-dimensional differential gel ..." dans: Human cell, Vol. 27, Issue 2, pp. 68-77, (2014) (PubMed).

Nordon, Hinchliffe, Malkawi, Pirianov, Torsney, Loftus, Cockerill, Thompson: "Comparative proteomics reveals a systemic vulnerability in the vasculature of patients with abdominal aortic aneurysms." dans: Journal of vascular surgery, Vol. 54, Issue 4, pp. 1100-1108.e6, (2011) (PubMed).

Détails sur Annexin a1

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Autre désignation: ANXA1

Sujet:

Background Information: ANXA1 encodes a protein that belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

Gene Name: Annexin A1

Alternative Symbols: ANX1, LPC1

Protein Name: Annexin RuleBase RU003540

Poids moléculaire: 39 kDa

ID gène: 301

NCBI Accession: NP_000691

UniProt: P04083

Pathways: Hormone Transport