Annexin a1 anticorps (N-Term)

N° du produit ABIN2774833

Détail du produit anti-Annexin a1 anticorps

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Annexin a1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: WFIENEEQEY VQTVKSSKGG PGSAVSPYPT FNPSSDVAAL HKAIMVKGVD

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 83%, Rat: 82%

Attributs du produit: This is a rabbit polyclonal antibody against ANXA1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 346 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Annexin a1 (ABIN2774833)

Ishida, Yamasaki, Yukizaki, Nishiyama, Tsubouchi, Okayama, Kataoka et al.: "Carnosol, rosemary ingredient, induces apoptosis in adult T-cell leukemia/lymphoma cells via glutathione depletion: proteomic approach using fluorescent two-dimensional differential gel ..." dans: Human cell, Vol. 27, Issue 2, pp. 68-77, (2014) (PubMed).

Nordon, Hinchliffe, Malkawi, Pirianov, Torsney, Loftus, Cockerill, Thompson: "Comparative proteomics reveals a systemic vulnerability in the vasculature of patients with abdominal aortic aneurysms." dans: Journal of vascular surgery, Vol. 54, Issue 4, pp. 1100-1108.e6, (2011) (PubMed).

Détails sur Annexin a1

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Autre désignation: ANXA1 (ANXA1 Produits)

Synonymes: anticorps anx1a, anticorps anxa1, anticorps wu:fa01d11, anticorps wu:fa05d11, anticorps wu:fk69h01, anticorps MGC64363, anticorps anx1, anticorps lpc1, anticorps MGC89164, anticorps ANXA1, anticorps ANX1, anticorps LPC1, anticorps p35, anticorps Anx-1, anticorps Anx-A1, anticorps C430014K04Rik, anticorps Lpc-1, anticorps Lpc1, anticorps Anx1, anticorps annexin A1a, anticorps annexin A1, anticorps annexin A1 L homeolog, anticorps Annexin A1, anticorps anxa1a, anticorps anxa1, anticorps anxa1.L, anticorps ANXA1, anticorps LOC100335033, anticorps Anxa1

Sujet: ANXA1 encodes a protein that belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
Alias Symbols: ANX1, LPC1
Protein Interaction Partner: UBC, MEIS2, SUMO2, SUMO3, WWOX, ZBTB1, HECW2, YWHAQ, ATP4A, UBD, BAG3, HMGA1, VCAM1, ITGA4, FN1, ATF2, ANXA4, RIPK1, IKBKG, RELA, CUL5, CDK2, SIRT7, ANXA5, ANXA1, KLHL23, LRIF1, OTUB1, C1orf123, CSAD, C14orf1, FAF1, COPS6, CCT7, KMT2B, UNC119, SUMO1, UBE2
Protein Size: 346

Poids moléculaire: 38 kDa

ID gène: 301

NCBI Accession: NM_000700, NP_000691

UniProt: P04083

Pathways: Hormone Transport