GJB1 anticorps (C-Term)

N° du produit ABIN2774855

Cet anticorps Lapin Polyclonal détecte spécifiquement GJB1 dans WB et IHC. Il présente une réactivité envers Humain, Rat, Souris, Chien, Boeuf (Vache), Cheval, Lapin et Cobaye et a été mentionné dans 1 publication.

Aperçu rapide pour GJB1 anticorps (C-Term) (ABIN2774855)

Antigène: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GJB1 anticorps

Épitope: C-Term

Séquence: GFGHRLSPEY KQNEINKLLS EQDGSLKDIL RRSPGTGAGL AEKSDRCSAC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GJB1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human GJB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 283 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GJB1 (ABIN2774855)

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." dans: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Détails sur GJB1

Antigène: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Autre désignation: GJB1

Sujet: This gene encodes for a Connexin 32 protein. A large Charcot-Marie-Tooth disease family has been identified with a novel mutation in the Cx32 P2 promoter region at position -526bp. Cx32 mutants that are associated with a CNS phenotype may have toxic effects in oligodendrocytes.
Alias Symbols: CMTX, CX32, CMTX1
Protein Interaction Partner: UBC, VKORC1, APP, CNST, OCLN, PRKACA, SRC, PRKCA, GJB2, CALM1, CAV1, JUP,
Protein Size: 283

Poids moléculaire: 31 kDa

ID gène: 2705

NCBI Accession: NM_000166, NP_000157

UniProt: P08034

Pathways: Cell-Cell Junction Organization