MCM7 anticorps (Middle Region)

N° du produit ABIN2774897

Cet anticorps Lapin Polyclonal détecte spécifiquement MCM7 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Cheval, Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour MCM7 anticorps (Middle Region) (ABIN2774897)

Antigène: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Reactivité: Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Cheval, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MCM7 anticorps

Épitope: Middle Region

Séquence: GGRSVRFSEA EQRCVSRGFT PAQFQAALDE YEELNVWQVN ASRTRITFV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MCM7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MCM7

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 389 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MCM7

Antigène: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Autre désignation: MCM7

Sujet: MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.
Protein Interaction Partner: AK8, MIPOL1, C8orf34, USHBP1, MCMBP, CCDC102B, TRIM54, MBIP, UBQLN1, TRIM27, NAB2, KIFC3, GOLGA2, PNMA1, UBC, SP2, HAUS2, CEP250, CEP57, SUMO2, SUMO3, PCNA, STAU1, SUZ12, RNF2, MCM4, MCM2, HSP90AB1, PRMT1, PRRC1, CLUH, TOMM34, TRIM16, HYOU1, BAG3, MIB1, P
Protein Size: 389

Poids moléculaire: 42 kDa

ID gène: 4176

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA