Klotho anticorps (N-Term)

N° du produit ABIN2774900

Cet anticorps anti-Klotho Polyclonal Lapin (ABIN2774900) détecte spécifiquement Klotho dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Lapin, Cheval, Boeuf (Vache) et Porc.

Aperçu rapide pour Klotho anticorps (N-Term) (ABIN2774900)

Antigène: Klotho (KL)

Reactivité: Humain, Souris, Rat, Lapin, Cheval, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Klotho est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Klotho anticorps

Épitope: N-Term

Fonction: Kl Antibody - N-terminal region

Séquence: GAAPSDSPIV VAPSGAPSPP LSSTGDVASD SYNNVYRDTE GLRELGVTHY

Homologie: Cow: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 91%, Rabbit: 92%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against Kl. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36671-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Klotho

Antigène: Klotho (KL)

Autre désignation: Kl

Sujet:

Background Information: Kl may have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. It may be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.

Gene Name: Klotho

Alternative Symbols: alp, alpha-kl

Protein Name: Klotho

Poids moléculaire: 116kDa

ID gène: 16591

NCBI Accession: NP_038851

UniProt: O35082

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding