WWP2 anticorps (Middle Region)

N° du produit ABIN2774931

L’anticorps Lapin Polyclonal anti-WWP2 a été validé pour WB et IHC. Il convient pour détecter WWP2 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Poisson zèbre (Danio rerio), Cheval et Mouton. Il y a 1 publication disponible.

Aperçu rapide pour WWP2 anticorps (Middle Region) (ABIN2774931)

Antigène: WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Poisson zèbre (Danio rerio), Cheval, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-WWP2 anticorps

Épitope: Middle Region

Séquence: EMKYTSEGVR YFVDHNTRTT TFKDPRPGFE SGTKQGSPGA YDRSFRWKYH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%, Zebrafish: 80%

Attributs du produit: This is a rabbit polyclonal antibody against WWP2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human WWP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 431 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-WWP2 (ABIN2774931)

Rougier, van Bemmelen, Bruce, Jespersen, Gavillet, Apothéloz, Cordonier, Staub, Rotin, Abriel: "Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins." dans: American journal of physiology. Cell physiology, Vol. 288, Issue 3, pp. C692-701, (2005) (PubMed).

Détails sur WWP2

Antigène: WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))

Autre désignation: WWP2

Sujet: WWP2 is a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. WWP2 contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions.This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: AIP2, WWp2-like
Protein Interaction Partner: LGALS9B, ANKRD44, FBXL18, VPS37C, PABPC1, RUSC1, HNRNPUL1, WWP2, PAIP1, TRAF4, FAM189A2, PDLIM7, EIF3A, WIPF1, UBE2L3, UBC, SNRPC, PTCH1, SMAD6, SMAD3, EZH2, PTEN, UBE2D3, FBXL15, RNF11, ARRDC1, ARRDC4, ARRDC3, VPS11, UBE2G1, UBE2J2, UBE2E3, UBE2E1, UBE2D
Protein Size: 431

Poids moléculaire: 47 kDa

ID gène: 11060

NCBI Accession: NM_199424, NP_955456

UniProt: O00308

Pathways: Negative Regulation of Transporter Activity