JMJD2D anticorps (C-Term)

N° du produit ABIN2774949

Il existe 2+ publications pour ce produit. L’anticorps anti-JMJD2D Polyclonal Lapin est utilisé pour la détection de JMJD2D dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour JMJD2D anticorps (C-Term) (ABIN2774949)

Antigène: JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JMJD2D est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-JMJD2D anticorps

Épitope: C-Term

Fonction: JMJD2D Antibody - C-terminal region

Séquence: SSTPGPSAQI IHPSNGRRGR GRPPQKLRAQ ELTLQTPAKR PLLAGTTCTA

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against JMJD2D. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human JMJD2D

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104665

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-JMJD2D (ABIN2774949)

Kim, Fuchs, Schwartz, Abdelhamid, Etter, Berry, Li, Ihnat, Li, Janknecht: "Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors." dans: American journal of translational research, Vol. 6, Issue 3, pp. 236-47, (2014) (PubMed).

Kim, Oh, Shin, Janknecht: "Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D." dans: PLoS ONE, Vol. 7, Issue 4, pp. e34618, (2012) (PubMed).

Détails sur JMJD2D

Antigène: JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

Autre désignation: JMJD2D

Sujet:

Background Information: JMJD2D belongs to JMJD2 family that is consist of four cancer-associated genes

Gene Name: Lysine (K)-specific demethylase 4D

Alternative Symbols: JMJD2D

Protein Name: Lysine-specific demethylase 4D

Poids moléculaire: 59kDa

ID gène: 55693

NCBI Accession: NP_060509

UniProt: Q6B0I6

Pathways: L'effet Warburg