JMJD2D anticorps (C-Term)

N° du produit ABIN183251

L’anticorps Lapin Polyclonal anti-JMJD2D a été validé pour WB. Il convient pour détecter JMJD2D dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour JMJD2D anticorps (C-Term) (ABIN183251)

Antigène: JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JMJD2D est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-JMJD2D anticorps

Épitope: C-Term

Séquence: SSTPGPSAQI IHPSNGRRGR GRPPQKLRAQ ELTLQTPAKR PLLAGTTCTA

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against JMJD2D. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human JMJD2D

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 523 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-JMJD2D (ABIN183251)

Kim, Fuchs, Schwartz, Abdelhamid, Etter, Berry, Li, Ihnat, Li, Janknecht: "Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors." dans: American journal of translational research, Vol. 6, Issue 3, pp. 236-47, (2014) (PubMed).

Kim, Oh, Shin, Janknecht: "Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D." dans: PLoS ONE, Vol. 7, Issue 4, pp. e34618, (2012) (PubMed).

Détails sur JMJD2D

Antigène: JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

Autre désignation: JMJD2D

Sujet: JMJD2D belongs to JMJD2 family that is consist of four cancer-associated genes
Alias Symbols: JMJD2D
Protein Interaction Partner: HECW2, PPP1CC, CUL4B, TP53, AR, KDM4D,
Protein Size: 523

Poids moléculaire: 59 kDa

ID gène: 55693

NCBI Accession: NM_018039, NP_060509

UniProt: Q6B0I6

Pathways: L'effet Warburg