Cyclin B3 anticorps (N-Term)

N° du produit ABIN2775035

Cet anticorps Lapin Polyclonal détecte spécifiquement Cyclin B3 dans WB. Il présente une réactivité envers Humain et Chien.

Aperçu rapide pour Cyclin B3 anticorps (N-Term) (ABIN2775035)

Antigène: Cyclin B3 (CCNB3)

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin B3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cyclin B3 anticorps

Épitope: N-Term

Séquence: MLLPLPPQSS KPVPKKSQSS KIVPSHHDPS EKTGENCQTK ISPSSLQESP

Homologie: Dog: 82%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CCNB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CCNB3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 291 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cyclin B3

Antigène: Cyclin B3 (CCNB3)

Autre désignation: CCNB3

Sujet: CCNB3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event.This cyclin may associate with CDC2 and CDK2 kinases, and be required for proper spindle reorganization and restoration of the interphase nucleus.The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chick and Drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and be required for proper spindle reorganization and restoration of the interphase nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: APP, CDK2,
Protein Size: 291

Poids moléculaire: 33 kDa

ID gène: 85417

NCBI Accession: NM_033670, NP_391990

UniProt: Q5HYQ1

Pathways: Cycle Cellulaire, Chromatin Binding