DUX4 anticorps (N-Term)
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- Antigène Voir toutes DUX4 Anticorps
- DUX4 (Double Homeobox 4 (DUX4))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DUX4 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TRGAEGTLGG RQGGREAGRN GGRDRATQGL GAGPREPGTD GGRKAGRKSG
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against DUX4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of human DUX4
- Top Product
- Discover our top product DUX4 Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- DUX4 (Double Homeobox 4 (DUX4))
- Autre désignation
- DUX4 (DUX4 Produits)
- Synonymes
- anticorps DUX4, anticorps DUX4L, anticorps double homeobox, 4, anticorps double homeobox 4, anticorps DUX4
- Sujet
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This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length, a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes, the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1, GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants.
Alias Symbols: DUX4L
Protein Size: 853 - Poids moléculaire
- 93 kDa
- ID gène
- 100288687
- NCBI Accession
- NM_001293798, NP_001280727
- UniProt
- Q9UBX2
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