DUX4 anticorps (N-Term)

N° du produit ABIN2775040

Cet anticorps anti-DUX4 Polyclonal Lapin (ABIN2775040) détecte spécifiquement DUX4 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour DUX4 anticorps (N-Term) (ABIN2775040)

Antigène: DUX4 (Double Homeobox 4 (DUX4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUX4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DUX4 anticorps

Épitope: N-Term

Fonction: DUX4 Antibody - N-terminal region

Séquence: TRGAEGTLGG RQGGREAGRN GGRDRATQGL GAGPREPGTD GGRKAGRKSG

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DUX4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human DUX4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36096-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DUX4

Antigène: DUX4 (Double Homeobox 4 (DUX4))

Autre désignation: DUX4

Sujet:

Background Information: This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length, a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes, the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1, GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants.

Gene Name: double homeobox 4

Alternative Symbols: DUX4L

Protein Name: double homeobox protein 4

Poids moléculaire: 93kDa

ID gène: 100288687

NCBI Accession: NP_001280727

UniProt: Q9UBX2