DDX21 anticorps (C-Term)

N° du produit ABIN2775198

Cité dans 2 publications. Cet anticorps anti-DDX21 Polyclonal Lapin (ABIN2775198) détecte spécifiquement DDX21 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Cheval, Chien, Porc, Boeuf (Vache), Cobaye et Lapin.

Aperçu rapide pour DDX21 anticorps (C-Term) (ABIN2775198)

Antigène: DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

Reactivité: Humain, Rat, Cheval, Chien, Porc, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX21 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DDX21 anticorps

Épitope: C-Term

Fonction: DDX21 Antibody - C-terminal region

Séquence: FRGQRDGNRR FRGQREGSRG PRGQRSGGGN KSNRSQNKGQ KRSFSKAFGQ

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DDX21. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DDX21

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8098604

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DDX21 (ABIN2775198)

Miyazawa, Yoshikawa, Magae, Ishikawa, Izumikawa, Terukina, Suzuki, Nakamura-Fujiyama, Miura, Hayano, Komatsu, Isobe, Takahashi: "Human cell growth regulator Ly-1 antibody reactive homologue accelerates processing of preribosomal RNA." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 19, Issue 4, pp. 273-86, (2014) (PubMed).

Romanova, Grand, Zhang, Rayner, Katoku-Kikyo, Kellner, Kikyo: "Critical role of nucleostemin in pre-rRNA processing." dans: The Journal of biological chemistry, Vol. 284, Issue 8, pp. 4968-77, (2009) (PubMed).

Détails sur DDX21

Antigène: DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

Autre désignation: DDX21

Sujet:

Background Information: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX21 encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.

Gene Name: DEAD (Asp-Glu-Ala-Asp) box helicase 21

Alternative Symbols: GUA, GURDB, RH-II/GU, RH-II/GuA

Protein Name: Nucleolar RNA helicase 2

Poids moléculaire: 86kDa

ID gène: 9188

NCBI Accession: NP_004719

UniProt: Q9NR30

Pathways: SARS-CoV-2 Protein Interactome