DDX23 anticorps (C-Term)
Aperçu rapide pour DDX23 anticorps (C-Term) (ABIN2775199)
Antigène
Voir toutes DDX23 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- EDSAVFYELK QAILESPVSS CPPELANHPD AQHKPGTILT KKRREETIFA
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against DDX23. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human DDX23
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 820 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DDX23 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23))
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Autre désignation
- DDX23
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Sujet
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DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex, it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.
Alias Symbols: prp28, PRPF28, U5-100K, U5-100KD
Protein Interaction Partner: SUMO2, STAU1, UBC, RPA3, RPA2, RPA1, ERG, SUZ12, WBP4, PRPF4B, PAXIP1, PHF5A, SF3A3, SART1, THOC5, PURA, RNU6ATAC, RNU4ATAC, TERF2IP, TERF1, SIRT7, HNRNPA1, SF3A2, SUMO1, Prpf8, TOP1, SNW1, TP63, TP73, MEPCE, USP39, PRPF4, OTUB1, RNPS1, CD2BP2,
Protein Size: 820 -
Poids moléculaire
- 90 kDa
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ID gène
- 9416
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NCBI Accession
- NM_004818, NP_004809
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UniProt
- Q9BUQ8
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Antigène
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