SNRNP200 anticorps (N-Term)

N° du produit ABIN2775221

Détail du produit anti-SNRNP200 anticorps

Antigène: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNRNP200 est non-conjugé

Application: Western Blotting (WB)

Séquence: GDEDVYGEVR EEASDDDMEG DEAVVRCTLS ANLVASGELM SSKKKDLHPR

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SNRNP200. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 2136 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SNRNP200

Antigène: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Autre désignation: SNRNP200 (SNRNP200 Produits)

Synonymes: anticorps ASCC3L1, anticorps BRR2, anticorps HELIC2, anticorps RP33, anticorps U5-200KD, anticorps small nuclear ribonucleoprotein U5 subunit 200, anticorps SNRNP200

Sujet: Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa.
Alias Symbols: ASCC3L1, BRR2, FLJ11521, HELIC2, RP33, U5-200KD
Protein Interaction Partner: PRPF8, EMD, CDKN1A, SUMO2, STAU1, UBC, SUMO1, LGR4, WWOX, RPA3, RPA2, RPA1, ERG, SUZ12, EZH2, EED, RNF2, rev, ELP3, KIAA1033, WDHD1, POLR2H, PIN1, USP34, TSC22D1, PARK2, FBXO6, TARDBP, PRPF4B, UBD, USP19, LSM8, SNRNP200, SF3B2, RBM5, ITGA4, FN1, RNF113A,
Protein Size: 2136

Poids moléculaire: 244 kDa

ID gène: 23020

NCBI Accession: NM_014014, NP_054733

UniProt: O75643

Pathways: Ribonucleoprotein Complex Subunit Organization