WRNIP1 anticorps (N-Term)
Aperçu rapide pour WRNIP1 anticorps (N-Term) (ABIN2775244)
Antigène
Voir toutes WRNIP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- WRNIP1 Antibody - N-terminal region
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Séquence
- PGAKRRRLSE SSALKQPATP TAAESSEGEG EEGDDGGETE SRESYDAPPT
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Homologie
- Cow: 79%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 79%, Rat: 100%, Yeast: 77%, Zebrafish: 85%
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Attributs du produit
- This is a rabbit polyclonal antibody against WRNIP1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human WRNIP1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36470-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 10, Issue 1, pp. 13-22, (2005) (PubMed).
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- WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
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Autre désignation
- WRNIP1
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Sujet
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Background Information: Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.
Gene Name: Werner helicase interacting protein 1
Alternative Symbols: WHIP, FAP93, CFAP93, bA420G6.2
Protein Name: ATPase WRNIP1
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Poids moléculaire
- 72kDa
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ID gène
- 56897
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NCBI Accession
- NP_569079
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UniProt
- Q96S55
Antigène
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